NaviSE: superenhancer navigator integrating epigenomics signal algebra
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منابع مشابه
Integrating epigenomics into pharmacogenomic studies
The goal of personalized medicine is to recommend drug treatment based on an individual's genetic makeup. Pharmacogenomic studies utilize two main approaches: candidate gene and whole-genome. Both approaches analyze genetic variants such as single nucleotide polymorphisms (SNPs) to identify associations with drug response. In addition to DNA sequence variations, non-genetic but heritable epigen...
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Epigenetics is one of the most rapidly expanding fields in biomedical research, and the popularity of the high-throughput next-generation sequencing (NGS) highlights the accelerating speed of epigenomics discovery over the past decade. Epigenetics studies the heritable phenotypes resulting from chromatin changes but without alteration on DNA sequence. Epigenetic factors and their interactive ne...
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www.landesbioscience.com Cell Cycle 3451 Epigenomic analyses are used for many applications, including discovering gene regulatory mechanisms, characterizing non-genetic transmission modes of adaptive and disease traits, identifying and detecting disease biomarkers, and for drug discovery, as epigenome modifying therapeutics are under development for therapeutic benefit. Epigenomic testing migh...
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Our paper presents an attempt to axiomatise signal processing. Our long-term goal is to formulate signal processing algorithms for an ideal world of exact computation and prove properties about them, then interpret these ideal formulations and apply them without change to real world discrete data. We give models of the axioms that are based on Gaussian functions, that allow for exact computatio...
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In the last years many mathematical software applications, that provide powerful tools for both numerical and symbolic calculations, have been developed. Although computer programs like Matlab, Mathematica or Maple are widely used in Lab classes at the university, they are seldom used as tools for teaching at university level. Also many dynamic geometry programs as Sketchpad or Cabri were devel...
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ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2017
ISSN: 1471-2105
DOI: 10.1186/s12859-017-1698-5